- Some individuals may be asymptomatic.
- Flu-like symptoms are possible and include:
- Vomiting, fatigue, chills, fever, sweats, and nausea,
- Blood clots, low blood pressure and abnormally low platelets may occur.
- Immunocompromised individuals, those missing a spleen or with preexisting liver or kidney conditions are at a higher risk to experience more severe symptoms.
Diagnosis and Treatment
- Clinical signs and a history of exposure are most often used for diagnosis.
- Jaundice, an abnormal increase in liver enzymes, an enlarged spleen or liver may indicate infection.
- A thin blood smear showing hemolytic anemia and Babesia in the red blood cells may also indicate infection.
- Diagnosis can be confirming via Polymerase Chain Reaction (PCR) detection of Babesia microti DNA in the blood.
- Antibodies specific to Babesia microti may be detected using an Indirect fluorescent antibody assay.
- Babesia duncani as a species of protozoan to cause Babesiosis in the US
CDC Treatment Recommendation
- Adult: Atovaquone 750mg- 2x daily with Azithromycin for 7-10 days or Clindamycin 600mg- 3x daily with Quinine 650mg- 3x daily for 7-10 days.
- Children: Atovaquone 20mg/kg- 2x daily with Azithromycin for 7-10 days or Clindamycin 7-10mg/kg every 3x daily with Quinine 8mg/kg- 3x daily.
- Babesia invades red blood cells and causes them to rupture leading to hemolytic anemia.