• Clinical signs and a history of exposure are most often used for diagnosis.
• Polymerase Chain Reaction may also assist in diagnosis by detecting the presence of Bartonella species DNA in serum.

CDC Treatment Recommendation

• Infection may resolve without intervention.
• The suggested dose of azithromycin is as follows:
• Adults and Children >45.5kg: 500mg on day 1 and 250mg for 4 days.
• Children < 45.5kg: 10mg/kg on day 1 and 5mg/kg for 4 days.

Disease Pathogenesis

• Bartonella henselae will infect endothelial cells and white blood cells leading to complications in the eyes, spleen nervous system, kidney, and bones if left untreated.
• A strong immune response typically results in disease symptoms and will resolve within 2-6 months.